Pilot Plant Engineer I (VPP) - Upstream

Company: CSL Seqirus
Location: Holly Springs
Posted on: March 23, 2026

Job Description:

Do you want to work with a company that tackles fascinating problems and find solutions to complex challenges? Seqirus has an exciting opportunity to join our expanding team in Holly Springs, NC. With an advanced manufacturing facility and expertise in influenza science we are one of the world leaders in the production of the influenza vaccine. We operate as one integrated global company, drawing together expert staff from different countries to collaborate. Together, we're working on the front line to protect communities from seasonal influenza and global pandemic threats. When you join Seqirus, you join a team dedicated to making a difference in people's lives. It's a feeling of possibility, creativity, and purpose that inspires us every day. You will be reporting to the Sr. Manager, Viral Pilot Plant and will work onsite at our CSL Seqirus site in Holly Springs, NC location. Benefits Include an annual bonus, Onsite Café, walking trail and other outdoor amenities, Medical, Dental, Vision, Life Insurance, 401K with a 6% match, and PTO available from your first day of hire. Responsibilities: Be the hands-on operator in material production within the Viral Pilot Plant Conduct all assigned activities in a safe and cGMP compliant manner. Prepare, and sterilizing production equipment Implement process steps according to defined SOPs, BPRs Document activities and review of documentation following cGMPs. Use electronic business systems (e.g, PLCs, LIMS, SAP). Follow site biosafety policy to handle biologically and chemically hazardous material. Work with maintenance, metrology, engineering, and quality. Solve process related issues, coordinating with appropriate teams to resolve issues and prevent reoccurrence. Complete process validations and short-term improvement projects, working with all the relevant parties to ensure accurate execution. Ensure protocols are performed as intended and oversee execution of protocols. Qualifications: Bachelor's degree required. Degree in Scientific discipline/Engineering preferred. 1 years of experience of downstream pharmaceutical manufacturing processes preferred. 1 or more years of experience in pharmaceutical/biotech operations working in a technical role Experience in column chromatography, Tangential flow chromatography, Ultracentrifugation, and other downstream processes in a commercial environment. Familiar with Unicorn software and Akta equipment LI-Onsite About CSL Seqirus CSL Seqirus is part of CSL. As one of the largest influenza vaccine providers in the world, CSL Seqirus is a major contributor to the prevention of influenza globally and a transcontinental partner in pandemic preparedness. With state-of-the-art production facilities in the U.S., the U.K. and Australia, CSL Seqirus utilizes egg, cell and adjuvant technologies to offer a broad portfolio of differentiated influenza vaccines in more than 20 countries around the world. To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/ . Our Benefits For more information on CSL benefits visit How CSL Supports Your Well-being | CSL . You Belong at CSL At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future. To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging Equal Opportunity Employer CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement . Watch our ‘On the Front Line’ video to learn more about CSL Seqirus

Keywords: CSL Seqirus, Chapel Hill , Pilot Plant Engineer I (VPP) - Upstream, Engineering , Holly Springs, North Carolina